IOP Lowering Effect of PLT Versus SLT in Naiv OAG Patients

University of Zurich (UZH)

Status: Unknown

Conditions: Open Angle Glaucoma,; Ocular Hypertension

Treatments: Device: Laser trabeculoplasty

Study type: Interventional

Funder types: Other

Identifiers

NCT01886456

14.1.2013_KEK ZH 2012-0422

Details and patient eligibility

About

To investigate the effect of patterned laser trabeculoplasty (PLT) compared to selective laser trabeculoplasty (SLT) on intraocular pressure (IOP) in treatment naiv patients suffering from open-angle glaucoma or ocular hypertension.

Values for IOP will be measured at baseline, 1 day and 1 month post-interventional as well as 2, 3, 6, 9, 12, 18 and 24 months after treatment.

• Trial with medical device

Enrollment: 210 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Intraocular pressure (treatment naiv or after 4 weeks wash-out phase) > 21 mm Hg
• visible angle structures over 360° on gonioscopy
• age = 18 years

Exclusion criteria

• Intraocular Inflammation
• patients who underwent refractive corneal surgery for any reason or who underwent ocular surgery to reduce intraocular pressure (e.g. trabeculectomy)
• monocle situation
• anterior chamber lenses (incl. iris claw)
• secondary glaucoma (with the exception of pseudoexfoliation and pigment dispersion)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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210 participants in 2 patient groups

PLT

Experimental group

Description:

patients treated with patterned laser trabeculoplasty

Treatment:

Device: Laser trabeculoplasty

SLT

Active Comparator group

Description:

patients treated with selective laser trabeculoplasty

Treatment:

Device: Laser trabeculoplasty