Iplasma IL6, Procalcitonin and VEGF and Dialysate Level in CAPD Patients

Bangkok Metropolitan Administration Medical College and Vajira Hospital

Status: Completed

Conditions: Chronic Kidney Disease

Treatments: Other: Measure plasma and dialysate level of IL-6, procalcitonin and VEGF

Study type: Observational

Funder types: Other

Identifiers

NCT02881892

041/57

Details and patient eligibility

About

The aim of study was to evaluated the correlation between plasma levels, dialysate appearance rate of VEGF, inflammatory cytokines (IL- 6, procalcitonin) and PSTR, dialysis adequacy in CAPD patients.

Full description

This cross -sectional study measured IL-6, procalcitonin and VEGF level in plasma and overnight effluent. PSTR of small solutes was evaluated by standard peritoneal equilibration test (standard PET). Weekly Kt/V and creatinine clearance (CCr ) were evaluated in all patients.

Enrollment: 26 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Stable CAPD patients without previous history of peritonitis

Exclusion criteria

• HIV
• Other infections, tuberculosis or on immunosuppressive drugs,
• Autoimmune disease,
• Cancer
• Diagnosis of permanent ultrafiltration failure .