iPod Games in Hepatic Encephalopathy

Hunter Holmes Mcguire Veteran Affairs Medical Center

Status: Completed

Conditions: Hepatic Encephalopathy; Cirrhosis

Treatments: Behavioral: ipod games

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT02154282

BAJAJ0013

Details and patient eligibility

About

To see if using ipod games can improve mental functioning

Enrollment: 30 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Cirrhosis proven by biopsy, radiology or endoscopy
• Age 18-70
• Able to give informed consent
• Cognitive dysfunction defined by impaired performance on standard cognitive tests

Exclusion criteria

• Illicit drug or alcohol use within 3 months
• Trans-jugular intra-hepatic porto-systemic shunt (TIPS) placement
• Need for psychoactive medications apart from continuous anti-depressants or methadone
• Any focal neurological deficit or neuro-muscular disease
• Inability to function with an iPod
• Inability to understand English

For MRI: inability to perform brain MRI is an exclusion

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

ipod games

Experimental group

Description:

Administered ipod games with cognitive testing before and after

Treatment:

Behavioral: ipod games