IPP-PSP Block vs. SPSIPB in Breast Surgery

Zonguldak Bulent Ecevit University

Status: Not yet enrolling

Conditions: Breast Cancer; Postoperative Acute Pain; Regional Anesthesia

Treatments: Procedure: Interpectoral-Pectoserratus Plane Block; Procedure: Serratus Posterior Superior Intercostal Plane Block

Study type: Interventional

Funder types: Other

Identifiers

NCT07246720

2025/16-9

Details and patient eligibility

About

This prospective, randomized clinical study aims to compare the analgesic efficacy of the interpectoral-pectoserratus plane block and the serratus posterior superior intercostal plane block for postoperative pain management in patients undergoing breast cancer surgery. Both techniques are ultrasound-guided regional anesthesia methods targeting different interfascial planes of the thoracic wall. The study will evaluate postoperative pain scores, opioid consumption, Quality of recovery and potential complications. The findings are expected to contribute to optimizing regional anesthesia strategies for enhanced recovery and improved analgesia following breast cancer surgery.

Enrollment: 70 estimated patients

Sex: Female

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• 18-65 years of age
• ASA I-II-III risk groups
• Patients with informed consent
• Patients undergoing breast cancer surgery

Exclusion Criteria: • Ages <18 and >65

• ASA ≥ IV
• History of allergy to local anesthetics
• Known coagulation disorders
• Infection near the insertion site
• Chronic analgesic use
• Patients with diabetes mellitus and those receiving neoadjuvant chemotherapy (due to potential impairment of pain sensation)
• Body mass index >30
• Dementia or confusion
• Lack of cooperation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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70 participants in 2 patient groups

Group IPP-PSP

Active Comparator group

Description:

Interpectoral-Pectoserratus Plane Block

Treatment:

Procedure: Interpectoral-Pectoserratus Plane Block

Group SPSIPB

Active Comparator group

Description:

Serratus Posterior Superior Intercostal Plane Block

Treatment:

Procedure: Serratus Posterior Superior Intercostal Plane Block