Iris Colors in Neonates: Do They Really Change? Prevalence, Predicting Factors and Associated Characteristics

Hillel Yaffe Medical Center

Status: Unknown

Conditions: Eye Color

Treatments: Other: Photograph

Study type: Interventional

Funder types: Other

Identifiers

NCT03072368

HYMC-0081-16

Details and patient eligibility

About

The goal of our study is to examine eye color at birth and the longitudinal change in eye color of preterm and full-term newborns.

Enrollment: 200 estimated patients

Sex: All

Ages: 2 days to 2 months old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Any baby born between the 24-42 week of gestation admitted to the well-baby nursery or the NICU whose parents have signed an informed consent.

Exclusion criteria

• Neonatal conjunctivitis
• Neonatal sepsis
• Inborn error of metabolism or genetic syndrome
• Eye abnormalities
• Parental refusal

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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200 participants in 4 patient groups

Blue eyes

Active Comparator group

Description:

50 babies born with blue eyes will be photographed and followed-up at baseline; 3 months and 12 months of age

Treatment:

Other: Photograph

Brown eyes

Active Comparator group

Description:

50 babies born with brown eyes will be photographed and followed-up at baseline; 3 months and 12 months of age

Treatment:

Other: Photograph

Green eyes

Active Comparator group

Description:

50 babies born with green eyes will be photographed and followed-up at baseline; 3 months and 12 months of age

Treatment:

Other: Photograph

Hazel eyes

Active Comparator group

Description:

50 babies born with hazel eyes will be photographed and followed-up at baseline; 3 months and 12 months of age

Treatment:

Other: Photograph