Irisin Expression and Gene Polymorphism in Type II Diabetic Patients With and Without CAD

Sohag University

Status: Completed

Conditions: Irisin Gene Polymorphism in Type II Diabetic Patients

Study type: Observational

Funder types: Other

Identifiers

NCT04957823

Soh-Med-21-06-20

Details and patient eligibility

About

This is an observertional study aimed at Study the association between the level of irisin expression and (Fibronectin Type III Domain Containing 5 (FDNC5) gene polymorphism and the presence and severity of coronary artery disease in patients with Type II DM.

Enrollment: 100 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• This study will include type II diabetic patients aged between 18 and 45 years old

Exclusion criteria

1. Recent acute myocardial infarction.
2. patients with Heart Failure
3. Active infection
4. End stage renal failure (GFR < 30 ml/min) or on dialysis
5. Liver cell failure
6. Athletes or having heavy muscular exercise in the previous 3 days

Trial design

100 participants in 2 patient groups

Diseased

Description:

type II diabetic patients with documented coronary artery disease.

Control

Description:

type II diabetic patients without coronary artery disease.