IRM Cognition in Patients With Head Trauma

University Hospital, Clermont-Ferrand

Status: Unknown

Conditions: Brain-damaged Patients

Treatments: Other: Cognitive rehabilitation program

Study type: Observational

Funder types: Other

Identifiers

NCT03181373

CHU-328

Details and patient eligibility

About

Longitudinal descriptive study of a cohort of twenty brain-damaged patients for a two years period.

Full description

The following data are collected in 3 months, 12 months then 24 months after the accident with followed data collection :

• Clinical, neuropsychological assessments
• Diffusion magnetic resonance imaging (MRI) for the reconstruction of anatomical pathways
• Functional imaging data.

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients, over the age of 18.
• Mild traumatic brain injury (Initial Glasgow score between 9 and 12)
• Severe brain injury (Initial Glasgow score between 3 and 8),
• Diffuse axonal injury and/or focal lesions.

Exclusion criteria

• Patients with MRI contraindications,
• Antecedents of brain lesions,
• Important lesions of the lobes and cortex on cerebral CT,
• Anoxic lesions related to cardiorespiratory arrest,
• Must be able to perform neuropsychological tests,
• Visual and auditory impairments.
• Aphasia

Trial design

20 participants in 1 patient group

Traumatic brain injury population

Description:

Defined population : traumatic brain injury population

Treatment:

Other: Cognitive rehabilitation program