ClinicalTrials.Veeva

Menu

Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or Schistosoma

F

Federal Institute of Technology (ETH) Zurich

Status

Completed

Conditions

Schistosoma Haematobium
Malaria, Falciparum
Hookworm Infections

Treatments

Dietary Supplement: Fe-57 orally, Fe-58 intravenously

Study type

Interventional

Funder types

Other

Identifiers

NCT01163877
EK-2009-N-19

Details and patient eligibility

About

The aim of this study is to investigate the change in iron metabolism in relation to malaria and helminth infections using a stable isotope technique.

Full description

The aim of the study is to determine how iron metabolism in subjects with infectious diseases (malaria, hookworm or S. haematobium) differs while infected and after treatment, i.e. the same individuals will be restudied while free of infection.

Enrollment

43 patients

Sex

All

Ages

12 to 16 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Children aged 12 to 16 years
  • Body weight > 30 kg
  • no chronic medical illnesses
  • no intake of vitamin/mineral supplements 2 weeks before the study and until the last blood drawing
  • For each of the 4 arms the respective disease needs to be present (symptomatic malaria, asymptomatic malaria, hookworm infection, S. haematobium infection) without any other concurrent infection

Exclusion criteria

Trial design

Primary purpose

Basic Science

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

43 participants in 4 patient groups

Symptomatic malaria infection
Other group
Treatment:
Dietary Supplement: Fe-57 orally, Fe-58 intravenously
Asymptomatic malaria infection
Other group
Treatment:
Dietary Supplement: Fe-57 orally, Fe-58 intravenously
Hookworm infection
Other group
Treatment:
Dietary Supplement: Fe-57 orally, Fe-58 intravenously
Schistosoma haematobium infection
Other group
Treatment:
Dietary Supplement: Fe-57 orally, Fe-58 intravenously

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2025 Veeva Systems