Iron Absorption From GDS Capsules II

Federal Institute of Technology (ETH) Zurich

Status: Completed

Conditions: Iron Deficiency

Treatments: Dietary Supplement: GDS capsule with meal; Dietary Supplement: Ferrous sulfate with meal

Study type: Interventional

Funder types: Other

Identifiers

NCT01985386

EK 2013-N-05-2

Details and patient eligibility

About

Slow release iron capsules containing ferrous sulfate have been designed based on the gastric delivery system. Iron absorption from those capsules administered with and without meals will be measured using stable iron isotopes.

Enrollment: 8 patients

Sex: Female

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• female,
• age 18-50 years,
• max. body weight 65 kg,
• serum ferritin < 30 µg/l

Exclusion criteria

• pregnancy,
• lactation,
• regular intake of medication,
• blood donation or significant blood losses over the past 4 months

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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8 participants in 2 patient groups

GDS (gastric delivery system), meal

Experimental group

Description:

GDS capsule with meal

Treatment:

Dietary Supplement: GDS capsule with meal

Ferrous sulfate, meal

Active Comparator group

Description:

Ferrous sulfate with meal

Treatment:

Dietary Supplement: Ferrous sulfate with meal