Iron Bioavailability From MyPyramid Menus

USDA Grand Forks Human Nutrition Research Center

Status: Completed

Conditions: Nonheme Iron Absorption

Treatments: Behavioral: My Pyramid menu days 1, 2, 3, 4, 5, 6 or 7

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT00754234

GFHNRC003

Details and patient eligibility

About

This study will measure nonheme iron absorption from each of the 7 daily MyPyramid menus. Such measurements will confirm whether modifications are needed to meet dietary iron recommendations and will provide data useful for validation algorithms to calculate dietary iron bioavailability.

Full description

Nonheme iron absorption is measured with 59Fe tracer added to a 1-day menu, with iron retention detected two weeks later in a whole body scintillation counter. Each subject has iron absorption measured from each of 7 1-d menus formulated to meet the US dietary guidelines (MyPyramid menus), with the order of menus randomly assigned. Each subject participates for 14 wk to test all 7 menus.

Enrollment: 16 patients

Sex: Female

Ages: 21 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women 21 to 50 years old

Exclusion criteria

• Anemia,
• High blood pressure,
• Disorders affecting iron absorption or retention,
• Underlying medical conditions,
• Taking medication other than birth control pills or hormone replacement therapy,
• Pregnancy,
• Daily use of analgesics

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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16 participants in 1 patient group

MyPyramid Menu Days 1-7

Experimental group

Description:

Iron absorption measured from one of the 7 different USDA MyPyramid menus for 1 day each, in randomized order for each subject, separated by 2 weeks

Treatment:

Behavioral: My Pyramid menu days 1, 2, 3, 4, 5, 6 or 7