Iron Therapy in Patients With End-Stage Renal Disease

Kaohsiung Medical University

Status: Unknown

Conditions: Anemia; Inflammation; Cardiovascular Risk Factor; End-stage Renal Disease

Treatments: Drug: irone sucrose

Study type: Interventional

Funder types: Other

Identifiers

NCT04491916

KMUHIRB-F(I)-20190110

Details and patient eligibility

About

This study will compare the clinical outcome of patients with maintenance dialysis room after changing the iron treatment guidelines from original upper limit with ferritin>500ng/ml, or TSAT>20% to Ferritin> 800ng / ml, or TSAT> 50%.

Full description

After two years of treatments, we will compare the incidence of clinical events, monthly blood, and biochemical examination data for the two years before and after the change.

Enrollment: 200 estimated patients

Sex: All

Ages: 20 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients receiving maintenance dialysis

Exclusion criteria

• less than 20 year-old, oncological patients undergoing chemotherapy, abnormal liver function, infection

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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200 participants in 1 patient group

Iron Treatment

Experimental group

Description:

Treatment with iron sucrose with orginal guideline from ferritin\>500ng/ml, or TSAT\>20% to ferritin\>800ng/ml, or TSAT\>50%.

Treatment:

Drug: irone sucrose