Irritable Bowel Syndrome and Low FODMAP Diet (FructIBS)

University Hospital, Rouen

Status: Completed

Conditions: Irritable Bowel Syndrome

Treatments: Other: Low FODMAPS diet

Study type: Interventional

Funder types: Other

Identifiers

NCT02188680

2013/011/HP

Details and patient eligibility

About

The patients having a syndrome SII would be more intolerant in the fructose than the healthy subjects and would benefit from a fructose diet but also from the fructans which contain some fructose. The intolerance in the fructose is diagnosed thanks to a respiratory test after absorption of fructose. However, the eviction of the fructose is sometimes recommended to the patients without having realized beforehand the test of intolerance.

Full description

The main objective is to evaluate the efficacy of the FODMAPS diet on IBS symptoms and to correlate the results with the respiratory test

Enrollment: 112 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• older than 18, patients with IBS, patients with no organic disorders, patients informed and agreed to participate

Exclusion criteria

• patients with sclerodermia, diabetes, obesity, anorexia, colo-rectal surgery, patients with small intestinal bacterial overgrowth, pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

112 participants in 2 patient groups

Low FODMAPS diet and positive breath testing for fructose

Active Comparator group

Description:

Patients with breath testing positive have a low FODMAPS diet. The test will be considered as positive if we observe an increase of more than 20 ppm of H2 and/or CH4 on a sample with regard to the basal concentration

Treatment:

Other: Low FODMAPS diet

negative breath testing for fructose

Sham Comparator group

Description:

patients with negative breath test have a low FODMAPS diet

Treatment:

Other: Low FODMAPS diet