Is Adipose Tissue a Reservoir for SARS-Cov2 Spread in Covid-19 Patients? (TA/SARS-Cov2)

Centre Hospitalier Universitaire de Nice

Status: Completed

Conditions: Covid-19 Patients

Treatments: Procedure: biopsies of subcutaneous adipose tissue

Study type: Interventional

Funder types: Other

Identifiers

NCT04427878

20-PP-15

Details and patient eligibility

About

Resident cells of human adipose tissue express ACE2 and DPP4, receptors for SARS-Cov2. The hypothesis is that the virus may enter and spread in fat depots.

Enrollment: 5 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male or female ≥ 18 years old
• Patients testing positive for Covid19
• Patients affiliated to social security
• Signing of free and informed consent

Exclusion criteria

• Vulnerable persons (- minors,
• adults under guardianship or curatorship,
• pregnant women,
• persons deprived of their liberty,
• persons who do not master the French language)

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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5 participants in 1 patient group

patients with Covid-19

Experimental group

Treatment:

Procedure: biopsies of subcutaneous adipose tissue