Is Effective Preoxygenation in Elderly Patients Related to Position?

Ankara City Hospital

Status: Completed

Conditions: Anesthesia Intubation Complication

Treatments: Procedure: Head up positioning during preoxygenation

Study type: Interventional

Funder types: Other

Identifiers

NCT05659758

E1-22-2775

Details and patient eligibility

About

The purpose of this study is to investigate the effect of the head-up position of 20 and 30 degrees on the ETO2 reaching time of 85% and the desaturation time of 92% after intubation in elderly patients compared to the supine position.

Full description

Patients will be randomized into 3 groups. The patients will lay in the supine position, in the control group and 20 and 30 degrees head up position in other two groups. Each patient will be preoxygenated with well fitting anaesthesia face mask with FiO2 of 100% at least 6L of flow until the ETO2 reaches concentration of 85%. The angle (20 or 30 degrees) formed by the patients' bodies (hips and feet parallel to the ground, lifting the back from the ground plane) with the ground will be measured with a spirit level, angle meter, and confirmed with a smartphone application. The time to reach ETO2 85% by starting preoxygenation in patients will be measured and recorded with a stopwatch. When the target is reached, anesthesia induction will be performed and the patients will be intubated. After the start of the intubation attempt, the stopwatch will be started again, after intubation, the patient will be ventilated with a balloon once and the location of the tube will be confirmed, the circuit will be separated and SpO2 will be expected to go down to the level of 92 % and recorded during this time.

Enrollment: 156 patients

Sex: All

Ages: 65 to 95 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age above 65 years
• ASA 1-2

Exclusion criteria

• heart failure
• uncooperative
• patients refusing well fitting face mask before reaching EtO2 85%
• chronic lung disease
• anemia (hb<8gr/dl)
• BMI>40
• neurological sequela

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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156 participants in 3 patient groups

control

Other group

Description:

patients will be preoxygenated in supine position

Treatment:

Procedure: Head up positioning during preoxygenation

20 degree

Experimental group

Description:

patients will be preoxygenated in 20 degrees head up position

Treatment:

Procedure: Head up positioning during preoxygenation

30 degree

Experimental group

Description:

patients will be preoxygenated in 30 degrees head up position

Treatment:

Procedure: Head up positioning during preoxygenation