Is it Possible to Replace Fentanyl in Anesthesia for Minor Procedures?

Ain Shams University

Status: Completed

Conditions: Anesthesia

Treatments: Drug: Lidocaine; Drug: Fentanyl; Drug: Propofol; Drug: Cisatracurium; Drug: Ketamine

Study type: Interventional

Funder types: Other

Identifiers

NCT03806374

ASUH9418

Details and patient eligibility

About

To compare between fentanyl group and ketamine lidocaine group for induction of anesthesia as regards hemodynamics and smooth intubation.

Full description

Two groups each with 60 patients Group I anesthesia initiated by propofol, fentanyl and cisatracurium. Group II anesthesia initiated by ketamine, lidocaine, propofol and cisatracurium.

Enrollment: 120 patients

Sex: All

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ASA I and II between
• Age between 18-55 years
• Undergoing minor surgical procedure less than an hour.

Exclusion criteria

• Patients with hypertension
• Patients with Ischemic heart diseases
• Patients with chronic renal or liver diseases

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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120 participants in 2 patient groups

Fentanyl

Active Comparator group

Description:

Administered propofol and fentanyl for induction.

Treatment:

Drug: Cisatracurium

Drug: Fentanyl

Drug: Propofol

Ketamine and lidocaine

Active Comparator group

Description:

Administered propofol, ketamine and lidocaine for induction.

Treatment:

Drug: Cisatracurium

Drug: Ketamine

Drug: Lidocaine

Drug: Propofol