Is Recombinant Growth Hormone Therapy Associated With Increased Intraoccular Pressure?

Shamir Medical Center (Assaf-Harofeh)

Status: Unknown

Conditions: Growth Hormone Treatment; Glaucoma

Treatments: Other: Measuring intraoccular pressure

Study type: Observational

Funder types: Other

Identifiers

NCT00867971

162/08

Details and patient eligibility

About

Recombinant growth hormone is a common therapy in the pediatric population. A number of associated side effects have been described. Several years ago, a case report was published concerning a child that was treated with RGH and developed acute glaucoma. To date no study has evaluated the connection.

Enrollment: 100 estimated patients

Sex: All

Ages: 6 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 6-18 years
• treatment with recombinant growth hormone

Exclusion criteria

• Underlying Chronic diseases
• Family history of eye diseases
• elevated occular pressure prior to starting treatment

Trial design

100 participants in 2 patient groups

RGH treated

Treatment:

Other: Measuring intraoccular pressure

Starting treatment with RGH

Treatment:

Other: Measuring intraoccular pressure