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Is Redo Pediatric Cardiac Surgery a Risk Factor for Transfusion?

C

CHU Brugmann University Hospital

Status

Completed

Conditions

Pediatric Cardiac Surgery
Transfusion

Treatments

Other: Redo op

Study type

Observational

Funder types

Other

Identifiers

NCT04456751
CHUB_redoped

Details and patient eligibility

About

In pediatric cardiac surgery, transfusion requirements are associated with age, development status, pathology, type of surgical intervention and extracorporeal bypass. In adult cardiac surgery, reinterventions (redo)are clearly linked to higher transfusion rates. The investigators want to study if this association is also true in pediatric cardiac surgery.

Full description

Whereas in adult cardiac surgery, redo-interventions are clearly linked to a higher transfusion rate, this is not really known in paediatric cardiac surgery. In this retrospective study, the investigators will analyse our database for paediatric cardiac surgery patients aged 0-16 years and operated between 2002 and 2017. Patients with a single cardiac surgery will be compared to patients with a second cardiac operation under extracorporeal bypass. The investigators will test the variables for normal distribution using a Shapiro-Wilk test. Non normal distributed variables will be compared by a non-parametric test (Mann Whitney U), frequency analysis will be done by a Chi-Square test. A univariate analysis will determine predicting factors for transfusion. Factors with a P value < 0.1 will be analysed by a multivariate analysis to determine independent factors for transfusion. Odds with 95% confidence intervals will be calculated. A P value < 0.05 will be considered statistically significant.

Enrollment

2,439 patients

Sex

All

Ages

Under 16 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients between 0 and 16 years
  • Cardiac surgery with cardiopulmonary bypass

Exclusion criteria

  • Jehova's witness

Trial design

2,439 participants in 2 patient groups

No redo op
Description:
Patients with a single cardiac operation under extracorporeal bypass
Redo op
Description:
Patients with a redo cardiac operation under extracorporeal bypass
Treatment:
Other: Redo op

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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