Is Sheep Ghee Cardioprotective?

Shiraz University of Medical Sciences

Status: Completed

Conditions: Inflammation; Cholesterol; Metabolic Disorder

Treatments: Dietary Supplement: sheep ghee; Dietary Supplement: sunflower oil

Study type: Interventional

Funder types: Other

Identifiers

NCT05492279

98-01-01-22054

Details and patient eligibility

About

Normal volunteers were randomly received Sheep ghee or sunflower oil, and before and after the study lipid profile and HS-CRP were measured.

Full description

During outpatient clinic visits, potentially eligible individuals were screened for enrollment according to the inclusion and exclusion criteria.

Patients were randomly allocated into the treatment and control groups via the blocked randomization method.

The control group received a normal diet for eight weeks with 10 g of sunflower oil. In the treatment group, sunflower oil was replaced with 10 g of sheep ghee.

50 patients in each group were enrollment. Patients' information, including demographic data and the serum levels of fasting blood sugar (FBS), LDL, HDL, triglyceride (TG), and hs-CRP, were recorded in datasheets twice: once before treatment with sheep ghee and once eight weeks later.

Enrollment: 50 patients

Sex: All

Ages: 20 to 76 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy adults, seeking outpatient visit at professor kojuri cardiology clinic

Exclusion criteria

• any history of ischemic heart disease (IHD),
• coronary artery bypass grafting (CABG)
• percutaneous intervention (PCI)
• stroke
• peripheral vascular diseases
• use of anti-hyperlipidemic agents
• unwillingness to participate.
• Need of tight hyperlipidemia control.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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50 participants in 2 patient groups

intervention

Experimental group

Description:

10 gr Sheep ghee

Treatment:

Dietary Supplement: sheep ghee

control group

Active Comparator group

Description:

10 gr sunflower oil

Treatment:

Dietary Supplement: sunflower oil