Is There a Correlation Between the Pulmonary Artery Pressure and the Acceleration of the Flow in the Pulmonary Artery Evaluated by Transesophageal Echocardiography (TOE) ?

Public Assistance-Hospitals of Marseille (AP-HM)

Status: Unknown

Conditions: Ventilated Patients

Treatments: Other: the direct measure of the pulmonary pressures; Other: the measure TRVMAX; Other: the measure of the pulmonary artery

Study type: Interventional

Funder types: Other

Identifiers

NCT01947257

2013-19 (Other Identifier)

2013-A00730-45

Details and patient eligibility

About

The measure of the pulmonary artery pressure (PAP) is a very useful index in intensive care to estimate right ventricular after load. The reference technique for this measure is the right catheterism which is an invasive technique. It is possible to estimate the pulmonary artery pressure by using transthoracic echocardiography (TTE) which allows, using the continuous Doppler, the measure of maximum speed of tricuspid regurgitation (TRvmax). The measure of the TRvmax can however be difficult for intensive care patients with little echogenicity or impossible for those having no tricuspid leak. The evaluation of the tricuspid regurgitation is also particularly difficult using TOE. To avoid these drawbacks, one can use the analysis of the pulmonary ejection in the pulmonary artery (PAAT) with TOE. However, the data of the literature are controversial on this method and it was not validated in mechanically ventilated intensive care patients.

The aim of this work is to compare three methods of measure of the PAP: the measure TRVMAX (by means of the tricuspid leak) by transthoracic echocardiography, the measure of the TAAP by transesophageal ultrasound and the direct measure of the pulmonary pressures by right catheterization, in ventilated patients already monitored with a catheter in the right cavities for usual indications in intensive care (ARDS, shock). We shall analyze then the correlation between the TRVmax, the TAAP and the pressures measured by the right catheterism which serves as reference technique.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged over 18 years
• Admitted to intensive care
• Mechanically ventilated and sedated
• Carrying a right catheterization
• Making a ETO indicated by the medical team or doctor in charge of the patient

Exclusion criteria

• Patients under 18 years
• expectant mother
• Patients without health insurance
• Refusal to close

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

50 participants in 1 patient group

ventilated patients

Other group

Treatment:

Other: the measure TRVMAX

Other: the direct measure of the pulmonary pressures

Other: the measure of the pulmonary artery