Is Video-assisted Thoracoscopic Lobectomy a Clinical Alternative for Surgically Resectable Pathologic N2 NSCLC Patients

Tang-Du Hospital

Status: Completed

Conditions: Non-small Cell Lung Cancer

Treatments: Procedure: Thoracotomy lobectomy; Procedure: VATS lobectomy

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT03613467

W-TONG06

Details and patient eligibility

About

The study was designed to compare the safety and effectiveness of vedio-assisted thoracoscopic lobectomy with open lobectomy for patients with surgically resectable pathologic N2 non-small cell lung cancer

Full description

The is a multi-center retrospective study. Patients with pathologic N2 NSCLC who underwent VATS or open lobectomy between 2014 and 2017 were included into this study. Clinical data on patient demographic, clinical characteristics, treatment and clinical outcomes will be collected to evaluate the safety and effectiveness of video-assisted thoracoscopic lobectomy for pathologic N2 NSCLC.

Enrollment: 2,145 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with age > 18 years old;
• Patients with pathologically diagnosed non-small cell lung cancer;
• Patients underwent lobectomy by either VATS or thoracotomy between 2014 and 2017;
• Patients who received lymphadenectomy for all accessible lymph nodes;
• Patients with N2 lymph nodes (+) after surgeries;

Exclusion criteria

• Patients with second primary tumors or multiple primary tumors;
• Patients who received chest surgeries before hospitalization;
• Patients with superior pulmonary sulcus tumor

Trial design

2,145 participants in 2 patient groups

VATS lobectomy

Description:

Pathologic N2 NSCLC patients who received lobectomy by video-assisted thoracoscopic surgery

Treatment:

Procedure: VATS lobectomy

Thoracotomy lobectomy

Description:

Pathologic N2 NSCLC patients who received lobectomy by thoracotomy

Treatment:

Procedure: Thoracotomy lobectomy