Ischemic Preconditioning in Endurance Athletes

Maastricht University Medical Centre (MUMC)

Status: Completed

Conditions: Exercise

Treatments: Other: Remote ischemic preconditioning

Study type: Interventional

Funder types: Other

Identifiers

NCT01774461

METC12-2-038

Details and patient eligibility

About

The aim of this study is to investigate the effect of remote ischemic preconditioning on biochemical and functional indices of cardiac function induced by a 30 km run in healthy trained long distance runners.

Enrollment: 29 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Informed consent
• Healthy
• Age between 18 and 65 years
• Endurance-trained (two or more training sessions per week)

Exclusion criteria

• Not applicable

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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29 participants in 2 patient groups

Sham RIC

No Intervention group

Description:

Control treatment (sham RIC) will consist of four 5-minute simulated inflations of a blood pressure cuff placed on the upper arm. The inflations will be separated by 5-minute periods when the blood pressure cuff will be deflated.

Remote ischemic conditioning

Active Comparator group

Description:

Blood pressure cuff placed on upper arm and inflated to 200mmHg for 5 minutes then deflated for 5 minutes - this cycle is repeated a total of 4 times.

Treatment:

Other: Remote ischemic preconditioning