IV Lidocaine on Postoperative Pain and QOR on Morbid Obese Patients Undergoing Bypass Surgery

Northwestern University

Status: Completed

Conditions: Obesity; Pain

Treatments: Drug: Normal Saline; Drug: Lidocaine Infusion

Study type: Interventional

Funder types: Other

Identifiers

NCT01180660

STU00032300

Details and patient eligibility

About

Can Intraoperative systemic lidocaine decrease postoperative opioid consumption and improve quality of recovery after laparoscopic gastric bypass surgery? The hypotheses:does the use of intraoperative systemic lidocaine decrease postoperative opioid consumption and improve quality of recovery after laparoscopic gastric bypass surgery.

This study has the potential to confirm an opioid sparing strategy for morbid obese patients undergoing laparoscopic gastric bypass surgery. The high incidence of obstructive sleep apnea and the increased risk of postoperative hypoxemia make the development of opioid sparing techniques in this patient population warranted.

Enrollment: 51 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA I, II,III;
• BMI > 35 kg/m2,
• Age between 18-70,
• Fluent in English,
• Patients undergoing laparoscopic gastric bypass,
• EKG within 3 months.

Exclusion criteria

• History of allergy to local anesthetics,
• History of chronic opioid use,
• Pregnant patients,
• History of EKG abnormalities.

Dropout: Conversion to open, patient or surgeon request.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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51 participants in 2 patient groups, including a placebo group

Lidocaine

Active Comparator group

Description:

Lidocaine infusion

Treatment:

Drug: Lidocaine Infusion

Placebo

Placebo Comparator group

Description:

Placebo Normal Saline Infusion

Treatment:

Drug: Normal Saline