Ivabradine Versus Propranolol for Induced Hypotension in Endoscopic Sinus Surgery

Ahmed talaat ahmed aly

Status and phase: Unknown; Phase 2

Conditions: Hypotension

Treatments: Drug: oral Propranolol; Drug: oral Ivabradine

Study type: Interventional

Funder types: Other

Identifiers

NCT04580342

ivabradine versus propranolol

Details and patient eligibility

About

the study is designed to compare the effect of addition of oral Ivabradine, propranolol to general anesthesia aimed reduction in blood loss during functional endoscopic sinus surgery.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age of 18 - 60 years.
• Patients of both genders.
• ASA grade I - II .

Exclusion criteria

• Patient refusal.
• Any contraindication to medication included in the study .
• Patients with allergy to medication included in the study.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Ivabradine group

Experimental group

Treatment:

Drug: oral Ivabradine

propranolol group

Experimental group

Treatment:

Drug: oral Propranolol