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Ivabradine Versus Propranolol for Induced Hypotension in Endoscopic Sinus Surgery

A

Ahmed talaat ahmed aly

Status and phase

Unknown
Phase 2

Conditions

Hypotension

Treatments

Drug: oral Propranolol
Drug: oral Ivabradine

Study type

Interventional

Funder types

Other

Identifiers

NCT04580342
ivabradine versus propranolol

Details and patient eligibility

About

the study is designed to compare the effect of addition of oral Ivabradine, propranolol to general anesthesia aimed reduction in blood loss during functional endoscopic sinus surgery.

Enrollment

60 estimated patients

Sex

All

Ages

18 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age of 18 - 60 years.
  • Patients of both genders.
  • ASA grade I - II .

Exclusion criteria

  • Patient refusal.
  • Any contraindication to medication included in the study .
  • Patients with allergy to medication included in the study.

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

60 participants in 2 patient groups

Ivabradine group
Experimental group
Treatment:
Drug: oral Ivabradine
propranolol group
Experimental group
Treatment:
Drug: oral Propranolol

Trial contacts and locations

1

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Central trial contact

Amal A Mohamed; Ahmed T Ahmed, A professor

Data sourced from clinicaltrials.gov

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