Ivermectin In Treatment of COVID 19 Patients

Ministry of Health and Population, Egypt

Status: Unknown

Conditions: Covid19

Treatments: Drug: Ivermectin

Study type: Interventional

Funder types: Other

Identifiers

NCT04425707

14-2020/3

Details and patient eligibility

About

as Egypt suffered a lot during the pandemic of COVID 19 with limited drug choices, many of the patients could not acheive viral clearence with the standard module of care teh idea of introduction of new medications in the treatment protocol of COVID 19 managment. Ivermectin had shown a promising results in vitro studies and in limited in vivo studies. this clinical trial may open a new hope for COVID 19 patients as a new and cheap line of treatment

Full description

the study will compare the effect of ivermectin in comaprison and addition to the standard mode of care for the COVID 19 patients

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Asymptomatic mild cases and moderate cases proven to be infected by COVID 19 by viral RNA swap

Exclusion criteria

• Contraindications for the drug: hypersensitivity.
• Any medications with possible drug interactions.
• Severe cases.
• Any malignant condition.
• Pregnant females.
• Breast feeding females.
• Any patient on the following medications: Erdafitinib- Lasmiditan- Quinidine due to potential severe drug interaction.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 3 patient groups

A ivermectin alone

Experimental group

Description:

ivermectin will be administarted alone to COVID 19 patients

Treatment:

Drug: Ivermectin

B standard care alone

Experimental group

Description:

standard care will be administarted alone

Treatment:

Drug: Ivermectin

C ivermectin added to standard of care

Active Comparator group

Description:

ivermectin will be administarted in adition to standard care

Treatment:

Drug: Ivermectin