Jackfruit Effects on Adipokines and Cognition in Boxers

Bayburt University

Status: Completed

Conditions: Brain-Derived Neurotrophic Factor (BDNF); Irisin; Cognitive Function; Omentin-1; Exercise Physiology; Adipokine Response

Treatments: Dietary Supplement: Jackfruit Supplement

Study type: Interventional

Funder types: Other

Identifiers

NCT07268976

BU-2025-01

Details and patient eligibility

About

This study investigates the effects of jackfruit oil extract on adipokine levels (Irisin, Omentin-1), brain-derived neurotrophic factor (BDNF), cognitive performance, and body measurements in healthy young boxers aged 18-25. Participants were randomly assigned to four groups receiving different doses of jackfruit oil extract (0, 100, 200, 300 mg/kg) or no supplement. Saliva samples, cognitive tests, and body measurements were collected at the start of the study and after 30 days to evaluate the outcomes.

Full description

This interventional study evaluates the effects of different doses of jackfruit oil extract on healthy young boxers aged 18-25. Participants were randomly assigned to four groups and followed for 30 days.

Saliva samples were collected to measure irisin, omentin-1, and BDNF levels. Cognitive performance was assessed using the Wisconsin Card Sorting Test and the Trail Making Test. Anthropometric parameters including weight, BMI, waist, hip, chest, limb circumferences, and body composition were measured at baseline and on day 30.

Statistical analyses were performed using SPSS version 26. ANOVA, Duncan, and Pearson correlation tests were used to determine significant differences and relationships between variables.

This study is randomized and controlled. Participants receive either one of three doses of jackfruit oil extract or no supplement. The follow-up period is 30 days.

Enrollment: 30 patients

Sex: All

Ages: 18 to 25 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male boxers aged 18-25 years
• Healthy individuals without any diagnosed chronic disease
• Participating in regular weekly boxing training
• Able to continue training throughout the study period
• Willing to voluntarily participate in the study
• Able to provide written and/or verbal informed consent

Exclusion criteria

• Presence of chronic diseases (e.g., diabetes, cardiovascular disorders)
• Any injury or musculoskeletal condition preventing continuation of training
• Known allergy or hypersensitivity to jackfruit or its components
• Use of medications or supplements that could interfere with study outcomes
• Individuals who refuse to provide informed consent

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

30 participants in 4 patient groups

J0 - Kontrol Grubu

No Intervention group

Description:

Katılımcılar hiçbir jackfruit yağı ekstresi almadı. Sadece normal diyet ve antrenman programlarını sürdürdüler.

J100

Experimental group

Description:

Katılımcılara 100 mg/kg jackfruit yağı ekstresi oral olarak 500 ml su içinde verildi. Müdahale 30 gün boyunca günlük olarak uygulandı.

Treatment:

Dietary Supplement: Jackfruit Supplement

J200

Experimental group

Description:

Katılımcılara 200 mg/kg jackfruit yağı ekstresi oral olarak 500 ml su içinde verildi. Müdahale 30 gün boyunca günlük olarak uygulandı.

Treatment:

Dietary Supplement: Jackfruit Supplement

J300

Experimental group

Description:

Katılımcılara 300 mg/kg jackfruit yağı ekstresi oral olarak 500 ml su içinde verildi. Müdahale 30 gün boyunca günlük olarak uygulandı.

Treatment:

Dietary Supplement: Jackfruit Supplement