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Joint Pain Occurring During Anti-TNF Therapy in Chronic Inflammatory Bowel Disease (ArthralgieMICI)

C

Centre Hospitalier Universitaire, Amiens

Status

Completed

Conditions

Inflammatory Bowel Diseases

Treatments

Other: diagnosis of joint

Study type

Observational

Funder types

Other

Identifiers

NCT02899871
PI2014_843_0016

Details and patient eligibility

About

IBD (inflammatory bowel disease) are associated with various types of joint manifestations, especially inflammatory. Patients with IBD treated with anti-TNF commonly report joint symptoms, with variable expressions and aetiologies, possibly responsible for impaired quality of life, and possibly leading to discontinuation of an effective and validated treatment.

Enrollment

99 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Males or females over the age of 18 years at the time of inclusion
  • Patients with IBD (Crohn's disease or ulcerative colitis), diagnosed by a set of compatible clinical (chronic diarrhoea, haematochezia, anoperineal lesions, etc.), laboratory, histological and endoscopic arguments. Patients will be included regardless of the severity of their disease, its clinical course, the type of lesions, and the presence or absence of associated manifestations.
  • Patients treated with anti-TNF: infliximab or adalimumab.
  • Informed patients not refusing to participate.
  • Patients covered by French national health insurance.

Exclusion criteria

  • Patients under the age of 18 years at the time of inclusion.
  • Patients previously treated with anti-TNF, but no longer treated with anti-TNF at the time of inclusion.
  • Protected majors (under permanent or temporary guardianship).

Trial design

99 participants in 2 patient groups

Control
Description:
patients treated with anti-TNF not presenting any joint symptoms.
Treatment:
Other: diagnosis of joint
case
Description:
aetiology of joint symptoms
Treatment:
Other: diagnosis of joint

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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