Juvenile Essential Arterial Hypertension and Vascular Function

Josip Juraj Strossmayer University of Osijek

Status: Unknown

Conditions: Child, Only; Essential Hypertension

Study type: Observational

Funder types: Other

Identifiers

NCT05109013

2158-61-07-21-06

Details and patient eligibility

About

The main goal of this study is to investigate the association of the juvenile essential arterial hypertension with systemic micro- and macrovascular reactivity and cerebral vascular function, and to examine the potential impact of elevated oxidative stress on this associations.

Enrollment: 50 estimated patients

Sex: All

Ages: 9 to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy normotensive children and children with essential arterial hypertension

Exclusion criteria

• secondary arterial hypertension
• other systemic diseases with immunopathology
• neurodegenerative diseasesat
• children that use therapy which has a high impact on vascular or immunological function (immunotherapy, immunosuppressive therapy, sistemic corticosteroid therapy etc..).

Trial design

50 participants in 2 patient groups

NT group - normotensive children

HT group - hypertensive children