Karyopharm Expanded Access Program for Selinexor (KEAP)

Karyopharm Therapeutics

Status

Conditions: Endometrial Cancer; Myelofibrosis; Sarcoma; Multiple Myeloma; Other; Diffuse Large B-Cell Lymphoma (DLBCL); Neuroglioblastoma; Peripheral T-cell Lymphoma

Treatments: Drug: selinexor

Study type: Expanded Access

Funder types: Industry; Other

Identifiers

NCT07215832

KEAP-KPT-330

Details and patient eligibility

About

KEAP is an expanded access program designed to provide selinexor to eligible participants outside of a clinical trial before the drug has been given marketing approval by the country's regulatory agency or the drug is commercially available in the country. Patients who do not qualify for an ongoing clinical trial but who might benefit from the investigational medicine may be eligible, provided they have exhausted all other available treatment options. Investigational medicines are provided to patients only through treating physicians who obtain the relevant approval on behalf of their patient from the relevant regulatory agency and follow all applicable safety-reporting regulations of the respective country.

Sex

Volunteers: No Healthy Volunteers

Inclusion criteria

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Exclusion criteria

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