Ketamine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain

Tanta University

Status: Completed

Conditions: External Oblique Intercostal Plane Block; Thoracotomy; Ketamine; Adjuvant; Pain

Treatments: Drug: 29 ml bupivacaine 0.25% + 1 ml saline; Drug: Ketamine

Study type: Interventional

Funder types: Other

Identifiers

NCT07138781

36264PR1282/7/25

Details and patient eligibility

About

The aim of this study is to evaluate the role of ketamine as an adjuvant in external oblique intercostal plane block for post thoracotomy pain.

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years.
• Both sexes.
• American Society of Anesthesiology (ASA) physical status I-III.
• Scheduled for open thoracotomy.

Exclusion criteria

• Patients with neurological or intellectual disability.
• Infection at the injection site.
• Opioid addiction.
• Allergic reaction to local anesthetics.
• Coagulation abnormalities.
• Drug abuse.
• Pregnancy.
• Severe liver and/or renal failure.
• Severe cardiovascular problems.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 2 patient groups

Group K

Experimental group

Description:

Patients will receive 29 ml bupivacaine 0.25% + 1 ml ketamine (50 mg) as a study group.

Treatment:

Drug: Ketamine

Group C

Active Comparator group

Description:

Patients will receive 29 ml bupivacaine 0.25% + 1 ml saline as a control group.

Treatment:

Drug: 29 ml bupivacaine 0.25% + 1 ml saline