Ketoacid Analogues Intradialytic Effect on Inflammation

RSUP Fatmawati

Status: Not yet enrolling

Conditions: Hemodialysis Complication

Treatments: Drug: Ketoacid

Study type: Interventional

Funder types: Other

Identifiers

NCT06392516

RSF_IPDGH_01

Details and patient eligibility

About

this study tries to measure the effect of intradialytic ketoacid analogues on inflammatory parameters

Full description

this study will measure inflammation parameters:

• interleukin 6
• malnutrition inflammation score
• neutrophil lymphocyte ratio
• monocyte lymphocyte ratio
• thrombocyte lymphocyte ratio

the duration of intervention is 12 weeks

Enrollment: 86 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient who undergo hemodialysis two times a week

Exclusion criteria

• travelling hemodialysis
• acute conditions
• HIV patient
• acute infection
• stroke and immobilized patient

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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86 participants in 2 patient groups

control

No Intervention group

Description:

patient who undergo hemodialysis two times a week

intervention

Experimental group

Description:

will be given parenteral ketoacid analogues intradialytics two times a week

Treatment:

Drug: Ketoacid