Ketoacidosis in Individuals With Type I Diabetes Mellitus (T1DM)

Charité University Medicine Berlin

Status: Completed

Conditions: Type 1 Diabetes

Treatments: Behavioral: Different insulin therapy at different time points

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00970567

EA4/039/07

Details and patient eligibility

About

The purpose of this study is to investigate individuals with type 1 diabetes who were disconnected from their insulin pump and insulin therapy was started again after positive ketones (U) in the urine or blood β-hydroxybutyrate.

Full description

Individuals with type 1 diabetes were disconnected from their insulin pump and insulin therapy was started again after positive ketones (U) in the urine or blood β-hydroxybutyrate with different therapy regimens after positive blood ketones.

Enrollment: 19 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• type 1 diabetes

Exclusion criteria

• severe hypo- or hyperglycemia during last 6 months
• acute illness

Trial design

19 participants in 3 patient groups

Arm 1

Other group

Description:

stop after positive ketone bodies in urine

Treatment:

Behavioral: Different insulin therapy at different time points

Arm 2

Other group

Description:

stop after positive ketone bodies in blood, normal therapy

Treatment:

Behavioral: Different insulin therapy at different time points

Arm 3

Other group

Description:

stop after positive ketone bodies in blood, additional therapy

Treatment:

Behavioral: Different insulin therapy at different time points