Ketohexokinase Isoforms in Endometrial Cancer.

Far Eastern Memorial Hospital

Status: Enrolling

Conditions: Endometrial Cancer

Treatments: Diagnostic Test: ketohexokinase

Study type: Observational

Funder types: Other; NETWORK

Identifiers

NCT03931265

108009-F

Details and patient eligibility

About

Our preliminary analysis with clinical database suggested that, in patients with type I endometrial cancer, high ketohexokinase-expressing group have lower survival probabilities than low ketohexokinase-expressing group. To understand the importance of ketohexokinase expression and isoform switch during the development of type I endometrial cancer, we propose a series of in vitro experiments and clinical examinations in this project.

Enrollment: 220 estimated patients

Sex: Female

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• >20 years
• Women with endometrial cancer who are about to be admitted to hospital for gynecological staging.
• Women who have undergone gynecological staging surgery for endometrial cancer in the past.

Exclusion criteria

• Women with endometrial cancer who receive preoperative chemotherapy or radiation therapy.