Ketoprofen With or Without Vaginal Isonicotinic Acid Hydrazide Prior to Hysterosalpingography

Aswan University Hospital

Status: Completed

Conditions: Infertility, Female

Treatments: Drug: Ketoprofen + placebo; Drug: Ketoprofen + INH

Study type: Interventional

Funder types: Other

Identifiers

NCT04500470

aswu/351/3/19

Details and patient eligibility

About

The aim of our study is to determine the efficacy of Ketoprofen with or without vaginal isonicotinic acid hydrazide on the pain scores during HSG.

Full description

hysterosalpingography can cause pain and discomfort in several ways: Use of the tenaculum to grasp the cervix and straighten the uterus for proper insertion; trans-cervical actions including measuring uterine depth, inserting the cannula; and injection of the dye

Enrollment: 200 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• any patient came for Hysterosalpingography

Exclusion criteria

• any patient has contraindication to HSG

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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200 participants in 2 patient groups, including a placebo group

Group A

Experimental group

Description:

patients will have of oral Ketoprofen 60 minutes before the procedure plus 3 table 900 mg vaginal isonicotinic acid hydrazide by the patient 12 hours before the procedure

Treatment:

Drug: Ketoprofen + INH

Group B

Placebo Comparator group

Description:

patients will have of oral Ketoprofen 60 minutes before the procedure plus 3 table vaginal placebo by the patient 12 hours before the procedure

Treatment:

Drug: Ketoprofen + placebo