KETOR: Effects of Peri Operative Administration of Ketamine on Long Term Post Thoracotomy Pain

Assistance Publique - Hôpitaux de Paris

Status and phase: Completed; Phase 3

Conditions: Chronic Post Thoracotomy Pain; Thoracotomy; Ketamine; Pain; Neuralgia

Treatments: Drug: Ketamine (or placebo : isotonic saline solution)

Study type: Interventional

Funder types: Other

Identifiers

NCT00224588

P990911

CRC99029

Details and patient eligibility

About

We assessed the effects of the N Methyl aspartate receptor antagonist Ketamine on long-term post thoracotomy pain. We hypothesized that ketamine could prevent supersensitization of the central nervous system involved in this chronic neuropathic pain.

Full description

In this clinical, randomized prospective study, peri operative administration of ketamine was compared to placebo on long term post thoracotomy pain after a 2 months follow up period.

Sex: All

Ages: 80+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients eligible for thoracotomy or pneumectomy

Exclusion criteria

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind