Kidney Function in Diabetics During CPB (Cardio Pulmonary Bypass) (DM-ECC)

Sahlgrenska University Hospital

Status: Suspended

Conditions: Diabetes Mellitus, Kidney, CPB

Treatments: Diagnostic Test: DM-ECC

Study type: Observational

Funder types: Other

Identifiers

NCT03405532

SahlgrenskaUHMT02

Details and patient eligibility

About

Filtration of urine in the kidney requires sufficient oxygen supply. The filtration of urine is greater in patents with diabetes. Our theory is that the diabetic kidney has a higher oxygen demand than the non diabetic kidney thereby making the diabetic kidney more sensitive to decreased oxygen delivery following reduced blood flow. With a catheter inserted into the kidney vein we will monitor the blood flow and oxygen saturation before and during CPB, in patient with diabetes.

Enrollment: 30 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with diabetes mellitus
• Serum creatinine < 150 micromol/L preoperative
• Heart surgery requiring CPB
• LV (left ventricle) EF >40 %
• Normal hemoglobin

Exclusion criteria