Kinesiophobia, Quality of Life, and Cognitive Functions in Fibromyalgia Syndrome

Bozyaka Training and Research Hospital

Status: Completed

Conditions: Kinesiophobia; Fibromyalgia; Cognitive Dysfunction

Study type: Observational

Funder types: Other

Identifiers

NCT04695288

01/12/2020-297

Details and patient eligibility

About

Although one of the most evidence-based treatment protocols is based on exercise strategies in patients with Fibromyalgia Syndrome, fear and avoidance of physical activity; named 'Kinesiophobia' may hinder the patients from the exercises. Cognitive dysfunctions are seen frequently in Fibromyalgia Syndrome. The aim of this study, to assess the relationship between kinesiophobia and cognitive functions, disease severity, quality of life, physical activity level, pain intensity, and anxiety/depression level in Fibromyalgia patients. Additionally, the investigators aimed to compare the kinesiophobia level and cognitive functions between patients with Fibromyalgia Syndrome and control subjects.

Full description

Cognitive dysfunction, including learning difficulties, memory, attention, and executive dysfunctions are frequent in fibromyalgia syndrome. Kinesiophobia is defined as fear and avoidance of physical activities, and it can lead to increased disability in patients with chronic pain. Although there is a relationship between cognitive functions and physical performance in Fibromyalgia Syndrome, the relationship between kinesiophobia, fibrofog, and quality of life are required to be investigated.

The aims of this study are:

1. To compare the kinesiophobia and cognitive functions in Fibromyalgia Syndrome with healthy volunteers
2. To examine the relationship between the severity of kinesiophobia, cognitive functions, disease activity, quality of life, physical activity level, depression and anxiety severity in Fibromyalgia Syndrome.

The hypothesis is, the patients diagnosed with Fibromyalgia Syndrome have higher kinesiophobia severity and worse cognitive functions, and also that kinesiophobia severity is associated with cognitive dysfunction, disease severity, physical activity level, and psychiatric symptoms in patients with Fibromyalgia Syndrome.

Enrollment: 160 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

-Fibromyalgia Syndrome

Exclusion criteria

• Education year < 5
• Inflammatory rheumatic disease
• Malignancy
• Psychiatric disease
• Alcohol/substance addiction
• Central nervous system disease
• History of head trauma
• Chronic pain conditions other than Fibromyalgia Syndrome

Trial design

160 participants in 2 patient groups

Fibromyalgia Syndrome

Description:

100 participants with a diagnosis of Fibromyalgia Syndrome according to the 2016 revised American College of Rheumatology diagnostic criteria.

Control subjects

Description:

60 healthy participants do not meet the exclusion criteria of the study.