Kinetics of Circulating Tumoral Cells in Bronchial Primitive Cancer

Fondation Hôpital Saint-Joseph

Status: Completed

Conditions: Bronchial Cancer

Treatments: Diagnostic Test: ISET® - Isolation by Size of Tumor cells

Study type: Interventional

Funder types: Other

Identifiers

NCT03328559

CTC

Details and patient eligibility

About

The pronostic value of Circulating Tumoral Cells(CTC) 's dosage by the method ISET® (tumoral cell isolation by size) in patients with bronchial cancer was previously demonstrated.

However, no kinetic study was ever realized to study the value of the CTC as predictive indicator of answer to the therapy. This project plans to study patients in an early stage and patients at advance stage locally moved forward or metastatic of the disease by evaluation of the presence and the number of CTC before every cure. This collaborative and original study should allow to refine the diagnoses of answer and to plan the possible relapses what would allow a premature institution of the treatment.

Enrollment: 6 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with non-small cell lung cancer
• accepting participation

Exclusion criteria

• refusing participation

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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6 participants in 2 patient groups

early stage bronchial cancer

Other group

Description:

Early stage which can benefit from a surgical resection. A taking will be made in preoperative then in every consultation of follow-up after the intervention

Treatment:

Diagnostic Test: ISET® - Isolation by Size of Tumor cells

Diagnostic Test: ISET® - Isolation by Size of Tumor cells

advanced stage bronchial cancer

Other group

Description:

Patients locally moved forward or at a metastatic stage handled by chemotherapy

Treatment:

Diagnostic Test: ISET® - Isolation by Size of Tumor cells

Diagnostic Test: ISET® - Isolation by Size of Tumor cells