Kinetics of Plasma Fibrinogen in Cardiac Surgery

Insel Gruppe AG, University Hospital Bern

Status: Completed

Conditions: Fibrinogens, Abnormal

Treatments: Procedure: Fibrinogen plasma level

Study type: Observational

Funder types: Other

Identifiers

NCT02605330

193/15

Details and patient eligibility

About

The study intends to measure fibrinogen plasma levels during the first 24 hrs in cardiac and thoracic surgical patients who undergo surgical procedures using extracorporeal circulation.

Enrollment: 26 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Elective patients undergoing coronary artery bypass grafting, aortic valve replacement or thoracic aortic surgery
• Signed written informed consent

Exclusion criteria

• Participation in another study
• Language barrier to understand study purposes (e.g. french as a native language)
• Preoperative low level of plasma fibrinogen (< 1.75 g/l)
• Preoperative anemia (Hb < 10g/dl)
• Emergency treatment
• Intake of anticoagulants other than aspirin within 14 days preceding surgery.
• Known coagulation disorder.
• Jehovah's witnesses

Trial design

26 participants in 3 patient groups

Fibrinogen plasma level in CABG

Description:

In all patients undergoing coronary artery bypass grafting (CABG) the investigators plan to measure the fibrinogen plasma level

Treatment:

Procedure: Fibrinogen plasma level

Fibrinogen plasma level in AVR

Description:

In all patients undergoing aortic valve replacement (AVR) the investigators plan to measure the fibrinogen plasma level

Treatment:

Procedure: Fibrinogen plasma level

Fibrinogen plasma level in AAR

Description:

In all patients undergoing aortic arch replacement (AAR) the investigators plan to measure the fibrinogen plasma level

Treatment:

Procedure: Fibrinogen plasma level