Korean Hereditary Breast Cancer Study (KOHBRA)

Korean Breast Cancer Study Group

Status: Unknown

Conditions: Breast Cancer; Ovarian Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT00595348

Sung-Won Kim, [e-mail]

KBCSG003

Details and patient eligibility

About

1. To evaluate the prevalence of BRCA1/2 mutation of breast cancer patients with family history of breast/ovarian cancer.
2. To evaluate the prevalence of BRCA1/2 mutation of breast cancer patients without family history, but high risk of hereditary cancer.
3. To evaluate the prevalence of BRCA1/2 mutation of family member of BRCA1/2 mutation.
4. To evaluate the prevalence of ovarian cancer of population of above 3 groups.

Full description

1. To find founder mutation in Korean
2. To correlation prevalence with risk evaluation
3. To find risk factors concerning life style

Enrollment: 2,250 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Over 19 years old
• Agree to this study
• Breast cancer patient with family history of breast/ovarian cancer (1 subgroup)
• Breast cancer patient; young age (<40), bilateral, male, combined ovarian (2 subgroup)
• Family members with 1, 2 subgroups (3 subgroup)

Exclusion criteria

• Under 20 years old
• Unable to decide for oneself