Krill Oil Study Compared to Fish Oil

University of Manitoba

Status

Completed

Conditions

Healthy Volunteers

Treatments

Dietary Supplement: Fish Oil

Dietary Supplement: Krill oil

Study type

Interventional

Funder types

Other

Industry

Identifiers

NCT01323036

B2011:014

Details and patient eligibility

About

The main purpose of the study is to evaluate the absorption of omega-3 fatty acids into the blood following consumption of krill oil compared with fish oil and placebo.

Full description

The main purpose of the study is to evaluate the absorption of omega-3 fatty acids into the blood following consumption of krill oil compared with fish oil and placebo. An additional purpose is to evaluate the lipid-lowering efficacy and safety of consumption of Krill Oil and Fish Oil to a placebo product. It has been shown that the ingestion of Krill Oil leads to better absorption of omega-3 fatty acids compared to ingestion of Fish Oil. It was also shown that consumption of krill oil and fish oil result in a favorable modification of lipid profiles. Therefore, it is anticipated that consumption of these krill oil and fish oil will improve lipid profile, as well as other health-related markers and will be safe and well tolerated.

Enrollment

24 patients

Sex

All

Ages

18 to 49 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

healthy men and premenopausal not pregnant or nursing women between 18 and 49 years old.

Exclusion criteria

smokers
rheumatoid arthritis
chronic illness
cardiovascular problems
dyslipidemia
liver and kidney disease
diabetes
endocrine or metabolic disease
inflammatory bowel disease
pancreatitis
gallbladder or biliary disease
neurological/psychological disease
bleeding disorders
experienced platelet abnormalities
gastrointestinal disorders that could interfere with fat absorption
hypertension
history of cancer
an intention to lose weight
use of anticoagulant
serum triglycerides (TG) >200 mg/dL, and/or total cholesterol (TC) >240 mg/dL, and/or LDL-cholesterol (LDL-C) >160 mg/dL
hypertension or lipid lowering medications
consumption of more than one alcoholic drinks/day
Consumption of more than one fish or seafood serving
one month prior to the start of the study
omega-6 fatty acids in the past 6 months
planned to consume seafood products or fish or to use any omega-3 or omega-6 fatty acids nutritional supplements at anytime in the duration of the study
planned to to become pregnant during the study period
BMI>28
allergies to fish seafood or corn