L-PRF in Alveolar Ridge Preservation

Rio de Janeiro State University

Status

Completed

Conditions

Bone Loss, Alveolar

Treatments

Procedure: Platelet-rich fibrin

Study type

Interventional

Funder types

Other

Identifiers

NCT03408418

72596717.3.0000.5259

Details and patient eligibility

About

The effect of leucocyte- and platelet-rich fibrin (L-PRF) for enhancing the healing after dental extractions is still a matter of debate. The available literature suggests that L-PRF performs positive effect to improve alveolar preservation resulting in less bone resorption on extraction sockets. L-PRF is a second generation of platelet concentrate produced without biochemical blood manipulation. L-PRF is composed by three key parameters: first, the presence of platelets; second, the presence of leucocytes; third, the density and complex organization of the fibrin matrix architecture produced by a natural polymerization process. The theory is that this key parameters acts to produce a faster bone healing.

Enrollment

48 patients

Sex

All

Ages

17 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

(1) Health patients, American Society of Anesthesiologists (ASA) I or II
(2) Patients who need to submit tooth extraction (pre-molar, canine and incisor teeth - uniradicular teeth or teeth with fused roots) which present ideal conditions to receive dental implants after 3 months.

Exclusion criteria