Labor Analgesia With Ropivacaine and Clonidine (LA)

UPECLIN HC FM Botucatu Unesp

Status: Completed

Conditions: Labor Pain

Treatments: Drug: ropivacaine and clonidine; Drug: ropivacaine

Study type: Observational

Funder types: Other

Identifiers

NCT00626977

upeclin/HC/FMB-Unesp-07

Details and patient eligibility

About

The aim of the present study was to examine, for pain relief during labor, the efficacy of two pharmacological approaches - the 0.125% ropivacaine alone and the 0.0625% ropivacaine added to 75 ug clonidine, both by epidural administration. The effect of the drugs on mother and newborn was also determined.

Enrollment: 32 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Singleton healthy
• Full-term pregnancy
• American Society of Anesthesiologists physical status I or II

Exclusion criteria

• Patients who had received opioids
• History of hypersensitivity to local anesthetic or to clonidine
• Fetus showed signs of possible intrauterine suffering
• Fetus showed signs of possible neurological deficit

Trial design

32 participants in 2 patient groups

R

Description:

R group:15 mL of 0.125% ropivacaine (18.75 mg)

Treatment:

Drug: ropivacaine

RC

Description:

RC group:0.0625% ropivacaine (9.375 mg) plus 75 ug clonidine

Treatment:

Drug: ropivacaine and clonidine