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Laboratory-based Hypnosis Intervention on Pain Responsivity in Adolescents With Sickle Cell Disease

University of California, Los Angeles (UCLA) logo

University of California, Los Angeles (UCLA)

Status

Completed

Conditions

Sickle Cell Disease

Treatments

Behavioral: Hypnosis
Behavioral: Attention Control

Study type

Interventional

Funder types

Other
NIH

Identifiers

NCT02987725
F32sarahmartin2

Details and patient eligibility

About

The purpose of this study is to test the effects of a laboratory-based hypnosis session compared to an attention control condition on peripheral blood flow, autonomic stress responses, and acute pain responses in adolescents (ages 12-21) with sickle cell disease, and examine how perceived disease-related stigma may affect these responses.

Enrollment

25 patients

Sex

All

Ages

12 to 21 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • A diagnosis of sickle cell disease
  • Age 12-21 years old
  • Fluent in English (the intervention will be delivered in English)
  • Participant is cognitively able to provide informed signed consent or assent
  • Participant is cognitively able to follow instructions

Exclusion criteria

  • Under 12 years of age or over 21 years of age
  • Not fluent in English
  • Pain medication prescription has changed or if they have been hospitalized for a vaso-occlusive episode within 30 days of study participation.
  • Diagnosis of a condition (e.g., neurological disorder affecting peripheral sensation, skin abnormality over the stimulus site, obstructive sleep apnea, diabetes, ischemic heart disease) or cognitive impairment that may affect data integrity or the ability to complete study procedures.

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

25 participants in 2 patient groups

Attention Control
Active Comparator group
Description:
Participants will listen to a 30-minute historical story.
Treatment:
Behavioral: Attention Control
Hypnosis
Experimental group
Description:
Participants will receive a 30-minute hypnosis session
Treatment:
Behavioral: Hypnosis

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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