Lactated Ringer's and PlasmaLyte in Critically Ill Adults

Sichuan University

Status: Unknown

Conditions: Critical Illness

Treatments: Drug: RL; Drug: PLA

Study type: Observational

Funder types: Other

Identifiers

NCT03813563

RL vs Plalyte

Details and patient eligibility

About

In recent years, there has been a large amount of literature reports that normal saline can increase the incidence of renal injury in critically ill patients compared with balanced salt solution.However, no studies have compared the effects of different types of balanced salt solutions on the incidence of renal injury.

Enrollment: 12,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients admitted to ICU

Exclusion criteria

• Patients <18 year old when admission
• Patients who stay less than 24 hours in ICU
• Patients who do not sufficient data for further analysis
• Readmission patients during the study period

Trial design

12,000 participants in 3 patient groups

Mix group

Description:

Patients who used two balanced salt solutions during icu stay

Treatment:

Drug: RL

Drug: PLA

RL group

Description:

Patients who have only used lactated Ringer's during icu stay

Treatment:

Drug: RL

PLA group

Description:

Patients who have only used PlasmaLyte during icu stay

Treatment:

Drug: PLA