Lactobacillus Rhamnosus and PCOS Treatment (ProjectPCOS)

Poznan University of Life Sciences

Status

Completed

Conditions

Hyperandrogenism

Polycystic Ovary Syndrome

Insulin Resistance

Obesity

Treatments

Dietary Supplement: Dietary group

Dietary Supplement: Lactobacillus group

Study type

Interventional

Funder types

Other

Identifiers

NCT03902301

Project PCOS

Details and patient eligibility

About

The effect of Lactobacillus rhamnosus supplementation on body weight, hyperandrogenism and insulin resistance in overweight and obesity women with Polycystic Ovary Syndrome will be analysed.

Enrollment

80 patients

Sex

Female

Ages

18 to 40 years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria:

patients diagnosed with PCOS,
BMI> 28 kg/m2 (overweight or obesity),
patients not participating in other similar research programs at the same time,
no previous operations on ovaries such as: laparoscopy, ovarian cautery etc.,
written agreement to take part in the research.

Exlusion criteria:

the use of antibiotics or probiotics within 6 months before the start of the experiment,
the use of pharmacological agents or hormones that may affect the course of the menstrual cycle or metabolic rate within 3 months,
the use of medicament that may affect on carbohydrate metabolism within 4 weeks,
failure to comply with dietary recommendations established during the nutritional intervention,
the use of weight loss supplements during the study,
clinical diagnosis of digestive disease (for example: irritable bowel syndrome, ulcerative colitis, Crohn's disease, celiac disease),
pregnancy and breast feeding.