Lactobacillus Rhamnosus GG in the Middle Ear and Adenoid Tonsil

Helsinki University Central Hospital (HUCH)

Status: Completed

Conditions: Acute Otitis Media; Upper Respiratory Infection

Treatments: Dietary Supplement: Lactobacillus rhamnosus GG

Study type: Interventional

Funder types: Other

Identifiers

NCT02110732

HelsinkiUCH

Details and patient eligibility

About

The purpose of this study is to evaluate the effect of oral administration of probiotic Lactobacillus rhamnosus GG in middle ear and adenoid tonsil.

Enrollment: 40 patients

Sex: All

Ages: 1 to 5 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• recurrent otitis media
• secretory otitis media
• chronic rhinitis
• recurrent sinusitis

Exclusion criteria

• significant illness

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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40 participants in 2 patient groups, including a placebo group

Lactobacillus rhamnosus GG

Active Comparator group

Description:

Lactobacillus rhamnosus GG 8-9 x 10 -9 pmy 2x2 for 3 weeks

Treatment:

Dietary Supplement: Lactobacillus rhamnosus GG

Crystalline cellulose

Placebo Comparator group

Description:

Crystalline cellulose

Treatment:

Dietary Supplement: Lactobacillus rhamnosus GG