Lactoferrin Versus Iron Supplement in Irondeficiency Anemia and Weight Loss in Obese Children

Ain Shams University

Status and phase: Completed; Phase 4

Conditions: Obesity, Childhood

Treatments: Drug: Iron Supplement

Study type: Interventional

Funder types: Other

Identifiers

NCT04014855

271182

Details and patient eligibility

About

The effect of lactoferrin versus iron supplement in treating iron deficiency anemia and helping weight loss in obese school age children

Full description

Comparing iron versus lactoferrin as regard iron defiency anemia and weight loss in obese children

Enrollment: 50 patients

Sex: All

Ages: 6 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1. children age will be between 6 -12 years old. 2. Presence of iron deficiency anemia, it will be diagnosed by

  • CBC >> Hemoglobin level concentration below 11.5 g/dl.

  • level of serum iron is below 30 µmol/l,

  • level of ferritin is below 15 µg/dl

  • Total iron binding capacity is more 480 µg/dlL. 3. children should be stable and free from chronic disease. 4. Body Mass index (BMI) should be ≥the 95th percentile for children and teens of the same age and sex.

    5. there is not history of iron supplements in the 3 months before treatment.

Exclusion criteria

1. Father/mother refuses to participate in the study.
2. Hospitalized patient.
3. Non-anemic patient.
4. Patients receiving iron supplements 3 months before enrollment.
5. Patients with chronic diseases.
6. personal or family history of allergy to cow's milk or infant formula, eczema, moderate-to-severe allergic rhinitis or asthma, or milk intolerance.
7. severe anemia as Hemoglobin level concentration below 7 g/dl.

Exclusion Criteria:

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 2 patient groups

obese children 1

Active Comparator group

Description:

iron supplementation

Treatment:

Drug: Iron Supplement

obese children 2

Active Comparator group

Description:

lactoferrin supplementation

Treatment:

Drug: Iron Supplement