Lakeshore Examination of Activity and Disability Exercise Response Study (LEADERS)

The University of Alabama at Birmingham

Status: Completed

Conditions: Stroke; Multiple Sclerosis

Treatments: Behavioral: Adapted Yoga; Behavioral: Movement to Music

Study type: Interventional

Funder types: Other

Identifiers

NCT02533882

F140821001

Details and patient eligibility

About

This study will examine the effectiveness of two types of group exercise classes on the health and functional status in inactive adults age 18-65 with neurological conditions including Multiple Sclerosis, stroke, and spinal cord injury (SCI). Participants will be randomly assigned to one of three groups; Movement to Music, Adapted Yoga, or a waitlist group who will complete a home-based exercise intervention of either Movement to Music or Adapted Yoga.

Enrollment: 180 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with stroke
• MS - mild to moderate disability (Patient Determined Disease Steps Score 0-6)
• Able to use arms or arms/legs for exercise
• Ambulatory or use manual wheelchair

Exclusion criteria

• Cognitive impairment (Mini-Mental State Exam score < 24)
• Recent weight change (+/- 25 pounds in 1 year)
• Poorly controlled blood pressure
• Cardiovascular disease event within the past six months
• Severe pulmonary disease
• Renal failure
• Current tobacco user or quit within the last six months
• Current use of medications for psychosis
• Active pressure ulcers

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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180 participants in 3 patient groups

Movement to Music

Experimental group

Description:

The Movement to Music classes are composed of a set of exercises tailored to the specific needs and capabilities of each target group. The class will consist of and aerobic component and a strength component performed to varying music tempos. All movements will be choreographed by qualified dance instructors.

Treatment:

Behavioral: Movement to Music

Adapted Yoga

Active Comparator group

Description:

Yoga classes will consist of postures adapted by qualified yoga instructors who have extensive experience in disability.

Treatment:

Behavioral: Adapted Yoga

Waitlist Control

No Intervention group

Description:

This group will receive biweekly newsletters on a variety of topics. At the end of this trial, they will receive a home based intervention.