Lamina Cribrosa Depth Change With Change in Eye Pressure

Johns Hopkins University

Status: Completed

Conditions: Glaucoma, Open-Angle

Treatments: Other: wearing swimming goggles or having laser suturelysis

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT03267849

IRB00133667

Details and patient eligibility

About

This is a study of the compliance of the lamina cribrosa with change in eye pressure.

Full description

Glaucoma patients and control subjects will have their internal eye structure (lamina cribrosa) imaged by optical coherence tomography (OCT) standard images at two different eye pressures. In some participants, the eye pressure will be changed by one of two interventions, wearing goggles or having laser suturelysis

Enrollment: 309 patients

Sex: All

Ages: 21 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• persons who consent to drink water and be imaged

Exclusion criteria

• non-consenting persons
• those who cannot be imaged

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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309 participants in 1 patient group

persons drinking water

Experimental group

Description:

all persons in the study will have images of the eye at baseline eye pressure, then the intervention will be to drink 2 bottles of water to increase eye pressure or decrease eye pressure, then will have images taken a second time

Treatment:

Other: wearing swimming goggles or having laser suturelysis