Language Acquisition in the Brain and Algorithms: Towards Systematic Monitoring of the Evolution of Semantic Representations in Biological and Artificial Neural Networks (SYNTAXE)

Fondation Ophtalmologique Adolphe de Rothschild

Status: Enrolling

Conditions: Language Acquisition in the Brain

Treatments: Other: intracranial brain recording

Study type: Observational

Funder types: NETWORK

Identifiers

NCT05217043

PBN_2021_25

Details and patient eligibility

About

Speech depends on our ability to recursively combine successive words into a complex sense. Although the order of these putative operations (syntax) has been the subject of extensive examination in the way in which the human brain learns to perform a "Semantic composition" remains largely unknown.

The Rothschild Hospital houses a unit specializing in drug-resistant epilepsy in children from 2 to 20 years old.

The identification of the epileptogenic zone often requires making an iEEG recording for a week (implantation of intracerebral electrodes in depth).

Sometimes this recording has to be repeated, providing a unique opportunity to directly record brain activity at different periods of its development.

Children will listen to pre-recorded phrases and stories such as "The Little Prince of Antoine de Saint-Exupéry" while being recorded with iEEG.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Any patient benefiting from a long-term intracranial brain recording.
• Non-opposition to participating in the study (adult patients)
• Non-opposition of at least one of the holders of the exercise of parental authority (minor patients)

Exclusion criteria

• Patient with complete deafness